Talon Runes & Matchups Guide - Mid Lane

Current Optimal Rune Setup (Patch 14.24):

• Primary: Domination
• Secondary: Sorcery
• Win Rate: 51.3%
• Pick Rate: 54.8%
• Based on 35,178 matches

Key Runes:

• Keystone: Electrocute
• Domination: Sudden Impact, Eyeball Collection, Relentless Hunter
• Sorcery: Nimbus Cloak, Absolute Focus

Unfavorable Matchups:

• Gragas (42.9% WR)
• Malphite (45.2% WR)
• Irelia (46.6% WR)
• Zoe (47.1% WR)
• Lissandra (47.2% WR)
• LeBlanc (47.5% WR)

Favorable Matchups:

• Smolder (58.0% WR)
• Malzahar (56.0% WR)
• Aurelion Sol (53.2% WR)
• Azir (53.2% WR)
• Fizz (53.1% WR)
• Lux (52.5% WR)

Best Duo Synergies:

• Gwen (56.4% WR)
• Fiddlesticks (55.1% WR)
• Bel'Veth (55.0% WR)
• Brand (55.0% WR)
• Ivern (54.8% WR)
• Rammus (54.6% WR)

Key Tips:

1. Prioritize early game aggression and look for first blood opportunities
2. Use flanking positions in teamfights to access enemy carries
3. Focus on picking off isolated targets, especially when they're warding
4. Utilize your ultimate (R) for both assassination and escape

For optimal performance, adapt your playstyle based on matchups and team composition while maintaining aggressive early game presence.

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