Galio Mid Lane Runes Guide

Current optimal rune setup combines Resolve (Primary) and Sorcery (Secondary), maintaining a 49.8% win rate across 34,736 matches in patch 15.4.

Primary Runes (Resolve):

• Keystone: Aftershock
• Demolish
• Second Wind
• Overgrowth

Secondary Runes (Sorcery):

• Manaflow Band
• Transcendence

Strong Matchups:

• Diana (55.6% WR)
• Katarina (54.6% WR)
• Mel (54.3% WR)
• Malzahar (54.1% WR)
• Akali (53.5% WR)
• Sylas (53.2% WR)

Weak Matchups:

• Swain (43.0% WR)
• Anivia (46.1% WR)
• Veigar (46.4% WR)
• Ahri (46.5% WR)
• Karma (46.7% WR)
• Ambessa (46.8% WR)

Best Jungle Synergies:

• Amumu (55.5% WR)
• Bel'Veth (53.8% WR)
• Warwick (53.2% WR)
• Gwen (53.1% WR)
• Darius (53.1% WR)
• Udyr (52.9% WR)

Key Tips:

1. Play conservatively post-level 6 as your ultimate provides utility rather than combat power
2. Manipulate wave position to facilitate jungle ganks
3. Before roaming with R, clear waves quickly using Q and E, followed by empowered auto-attack

This build prioritizes defensive capabilities while maintaining ability power scaling through secondary runes, making it effective for both lane sustainability and roaming potential.

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