Lee Sin runes and matchups guide for optimal jungle performance in patch 15.4.

Best Rune Setup - Precision/Inspiration Current Win Rate: 49.9% | Pick Rate: 83.2% (24,026 matches analyzed)

Primary Tree (Precision):

• Keystone: Conqueror
• Triumph
• Legend: Alacrity
• Coup de Grace

Secondary Tree (Inspiration):

• Magical Footwear
• Cosmic Insight

Counters Weakest Against:

• Darius (40.2% WR)
• Taliyah (42.7% WR)
• Briar (43.5% WR)
• Bel'Veth (44.1% WR)
• Rek'Sai (44.2% WR)
• Elise (44.3% WR)

Strongest Against:

• Nidalee (55.3% WR)
• Rammus (54.3% WR)
• Kha'Zix (54.0% WR)
• Rengar (53.9% WR)
• Evelynn (53.1% WR)
• Zed (53.1% WR)

Best Duo Synergies

• Kassadin (57.0% WR)
• Kayle (55.4% WR)
• Akshan (55.0% WR)
• Akali (54.4% WR)
• Vladimir (54.2% WR)
• Gangplank (54.1% WR)

Key Tips

1. Don't commit to every Q hit - evaluate the situation first
2. Start ganks with W instead of Q when possible
3. Save Q as follow-up CC or escape option
4. Flash-R priority targets into your team, avoid kicking tanks
5. Use R primarily to create advantages for your team, not just for damage

These optimal setups and strategies are based on high-elo gameplay analysis and current meta trends.

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