Jayce Optimal Runes Guide for Mid Lane

The strongest rune setup for Jayce in patch 15.3 features Resolve as primary and Inspiration as secondary tree, maintaining a 49.7% win rate across 4,950 matches.

Primary (Resolve):

• Keystone: Grasp of the Undying
• Demolish
• Bone Plating
• Overgrowth

Secondary (Inspiration):

• Magical Footwear
• Biscuit Delivery

Best Matchups:

• Volibear (54.0% WR)
• Sylas (53.5% WR)
• Aurora (53.0% WR)
• Akali (52.7% WR)
• Varus (51.8% WR)
• Cassiopeia (51.7% WR)

Challenging Matchups:

• Olaf (41.9% WR)
• Poppy (42.6% WR)
• Zac (43.2% WR)
• Warwick (43.7% WR)
• Dr. Mundo (44.6% WR)
• Yorick (44.7% WR)

Best Duo Synergies:

• Taliyah (57.1% WR)
• Karthus (51.8% WR)
• Gwen (51.7% WR)
• Nunu & Willump (50.9% WR)
• Udyr (50.7% WR)
• Volibear (50.5% WR)

Essential Tips:

1. Focus on poking with Q before engaging in direct fights
2. Position Q to hit both enemy champion and minions for efficient wave clear
3. Manage mana carefully - always reserve enough for defensive E
4. Use ranged form for poke and melee form for all-in combos
5. Coordinate ganks with junglers who have strong CC

Master these fundamentals to maximize Jayce's potential in the mid lane while maintaining consistent pressure and map control.

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