Grasp of the Undying is Gnar's most effective keystone rune for Mid lane in patch 15.3, maintaining a 47.3% win rate across 110 matches with a 41.5% pick rate.

Primary Runes (Resolve):

• Grasp of the Undying
• Demolish
• Bone Plating
• Overgrowth

Secondary Runes (Precision):

• Triumph
• Legend: Alacrity

Strong Matchups:

• Trundle (58.0% WR)
• Volibear (57.3% WR)
• Dr. Mundo (56.7% WR)
• Sion (56.3% WR)
• Poppy (56.3% WR)
• Pantheon (55.2% WR)

Weak Matchups:

• Zac (42.2% WR)
• Maokai (44.1% WR)
• Karma (44.7% WR)
• Cassiopeia (44.7% WR)
• Quinn (45.0% WR)
• Vayne (45.2% WR)

Best Synergies:

• Fiddlesticks (57.9% WR)
• Volibear (57.7% WR)
• Bel'Veth (55.0% WR)
• Karthus (54.4% WR)
• Skarner (54.2% WR)
• Wukong (52.7% WR)

This rune setup maximizes Gnar's trading potential in lane while providing essential scaling through Precision secondary runes. The combination of Grasp's sustain and Triumph's teamfight potential makes this build particularly effective for both lane dominance and late-game impact.

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