
Alistar Support Runes Guide: Best Setups for Patch 15.5

For Alistar Support in patch 15.5, the optimal rune setup achieves a 49.4% win rate with a 58.4% pick rate across 27,932 matches.
Primary Tree (Resolve)
- Keystone: Aftershock
- Demolish
- Second Wind
- Overgrowth
Secondary Tree (Inspiration)
- Hextech Flashtraption
- Cosmic Insight
Strong Against
- Tahm Kench (55.4% WR)
- Sylas (54.6% WR)
- Brand (54.2% WR)
- Mel (53.9% WR)
- Xerath (53.3% WR)
- Pyke (53.0% WR)
Weak Against
- Taric (43.8% WR)
- Soraka (44.7% WR)
- Janna (45.3% WR)
- Vel'Koz (45.4% WR)
- LeBlanc (46.8% WR)
- Seraphine (47.0% WR)
Best ADC Synergies
- Veigar (59.5% WR)
- Seraphine (57.7% WR)
- Kog'Maw (56.1% WR)
- Nilah (55.4% WR)
- Yasuo (53.2% WR)
- Smolder (52.4% WR)
Key Tips
- Position near your ADC during laning phase to threaten engagement
- Set up ambushes in bushes before major objectives using W>Q combo
- After engaging in teamfights, fall back to protect your ADC
Core Combo W>Q (Headbutt into Pulverize) is Alistar's primary engagement tool
This champion excels at engaging fights and protecting carries, making him a versatile support pick in the current meta.
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