Vayne Top Build Guide: Best Setups and Counters | 55.2% Win Rate

Vayne Top Build Guide: Best Setups and Counters | 55.2% Win Rate

By Marcus Chen

February 23, 2025 at 04:16 PM

Vayne Top Guide - Patch 15.4

Most Popular Build (55.2% WR, 1,208 matches)

  • Summoner Spells: Flash, Ghost
  • Runes: Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, Overgrowth
  • Core Items: Blade of The Ruined King > Berserker's Greaves > Guinsoo's Rageblade
  • Full Build: Add Terminus > Wit's End > Jak'Sho, The Protean
  • Skill Order: Q > W > E

Key Tips:

  • Maintain max range against melee champions
  • Focus on getting 3 auto-attacks for W passive proc
  • Save Q for defensive positioning in teamfights

Best Matchups:

  1. Rumble (65.6% WR)
  2. Riven (65.5% WR)
  3. Draven (62.5% WR)
  4. Pantheon (60.6% WR)
  5. K'Sante (59.8% WR)

Worst Matchups (Avoid):

  1. Quinn (35.1% WR)
  2. Vladimir (35.6% WR)
  3. Ornn (35.9% WR)
  4. Malphite (36.4% WR)
  5. Aurora (38.5% WR)

Best Support Synergies:

  • Zyra (57.9% WR)
  • Soraka (56.8% WR)
  • Milio (55.7% WR)
  • Zilean (55.7% WR)
  • Seraphine (54.6% WR)

Alternative Builds:

Second Popular Build (50.5% WR, 202 matches):

  • Same summoners and items
  • Key Change: Press the Attack keystone

Off-Meta Build (52.5% WR, 80 matches):

  • Same runes and summoners
  • Key Change: Kraken Slayer as first item

Situational Items:

  • Adjust defensive rune shards based on lane opponent
  • Build path should adapt to enemy team composition
  • Consider Mercurial Scimitar against heavy CC

Note: Build statistics based on Emerald+ ranked matches in current patch.

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