
Twitch Champion Guide: Ultimate ADC Assassin Guide for Patch 15.4.1
Champion Overview
Twitch, "The Plague Rat," is a unique assassin-marksman who excels at ambushing enemies and dealing devastating damage in teamfights. His invisibility and poison-based abilities make him a deadly threat when played correctly.
Core Abilities
Passive - Deadly Poison
- Basic attacks apply poison stacks
- Each stack deals damage over 6 seconds
- Stacks up to 6 times
- Reapplying refreshes duration
Q - Ambush
- Grants 10-14 seconds of camouflage
- Provides 30-50% attack speed after revealing
- Cooldown resets when poisoned enemies die
W - Poison Bottle
- Throws poison in target area
- Applies passive stacks
- Slows enemies 25-45%
- Contaminated zone lasts 3 seconds
E - Contaminate
- Deals damage to poisoned enemies
- Damage increases with poison stacks
R - Fire and Pray
- Lasts 6 seconds
- Grants 20-40 bonus AD
- Increases attack range by 300
- Attacks pierce through enemies
- Each hit can critically strike
Optimal Skill Order
- Level 1: Q (Ambush)
- Level 2: E (Contaminate)
- Max Priority: R > E > Q > W
Exception: Against difficult matchups, start W > E with Doran's Ring for safer farming.
Core Build Strategy
Essential Stats:
- Attack Damage
- Attack Speed
- Critical Strike
- Armor Penetration
- Lifesteal
Build Priority:
- Core damage items
- Attack speed items
- Defensive options based on matchup
Note: Full build requires minimum 4 items to reach maximum potential.
Laning Phase Tips
- Use invisibility to surprise enemies
- Stack poison before using Contaminate
- Position carefully due to low early mobility
- Focus on farming when against high-range opponents
This champion requires strong positioning and timing to maximize effectiveness in both lane phase and teamfights.
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