Neeko Runes Guide for Mid Lane - Patch 14.24

Optimal Rune Setup: Sorcery + Inspiration

• Win Rate: 52.3%
• Pick Rate: 44.4%
• Based on 7,813 matches

Primary Tree (Sorcery):

• Keystone: Arcane Comet
• Manaflow Band
• Transcendence
• Scorch

Secondary Tree (Inspiration):

• Biscuit Delivery
• Cosmic Insight

Strong Matchups:

• Zoe (55.9% WR)
• Swain (54.7% WR)
• Alistar (54.4% WR)
• Blitzcrank (53.3% WR)
• Brand (53.0% WR)
• Galio (52.3% WR)

Weak Matchups:

• Poppy (46.6% WR)
• Janna (46.8% WR)
• Zyra (47.2% WR)
• Sona (47.4% WR)
• Nami (47.9% WR)
• LeBlanc (48.1% WR)

Best Duo Synergies:

• Nilah (59.2% WR)
• Kog'Maw (54.5% WR)
• Miss Fortune (53.9% WR)
• Seraphine (53.5% WR)
• Samira (53.0% WR)
• Ezreal (52.6% WR)

Essential Tips:

1. Only transform when enemies haven't spotted you
2. Use W speed boost for Ultimate positioning in teamfights
3. Root duration increases when E passes through multiple minions first

Combat Combos:

• Basic Harass: E (root) > Q > Auto Attack
• All-in: E > Q > R > W (reposition) > Q
• Chase: W (speed boost) > E > Q > Auto Attack
• Escape: W (clone) > R (if needed) > Flash

Remember to adapt your rune choices based on specific matchups and team compositions for optimal performance.

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