Vayne is a high-skill marksman who excels at single-target damage and late-game scaling. Here's a comprehensive guide to mastering this champion.

Champion Matchups

Weak Against:

• Nilah (45.8% WR)
• Aphelios (49.4% WR)
• Lucian (49.7% WR)
• Caitlyn (49.7% WR)
• Varus (49.7% WR)
• Twitch (49.8% WR)

Strong Against:

• Mel (60.5% WR)
• Kai'Sa (54.4% WR)
• Ezreal (54.2% WR)
• Ziggs (54.1% WR)
• Sivir (53.9% WR)
• Smolder (53.5% WR)

Best Support Synergies:

• Zyra (57.9% WR)
• Soraka (56.3% WR)
• Milio (55.4% WR)
• Leona (55.3% WR)
• Zilean (55.1% WR)
• Seraphine (54.5% WR)

Key Tips for Success:

1. Focus on safe farming early game to reach your power spikes
2. Maximize W damage by landing three consecutive auto-attacks
3. Use Tumble (Q) defensively in teamfights rather than aggressively
4. Position carefully and stay behind your frontline
5. Scale into late game where you excel at tank-shredding

Core Strategy:

• Early Game: Play safe, focus on CS
• Mid Game: Look for isolated targets and duels
• Late Game: Position well in teamfights and target the closest enemy

For optimal performance, join Vayne communities to discuss strategies and stay updated on the latest professional builds through resources like LoLalytics.

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