Kai'Sa Bot Lane Guide: Best Builds, Runes, and Matchups (Patch 15.3)

Kai'Sa Bot Lane Guide: Best Builds, Runes, and Matchups (Patch 15.3)

By Marcus Chen

February 18, 2025 at 12:25 AM

Kai'Sa Build Guide for Patch 15.3

Best Popular Build (50.5% WR, 97,280 matches):

  • Summoner Spells: Flash, Barrier
  • Runes: Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace + Biscuit Delivery, Magical Footwear
  • Rune Shards: Attack Speed, Adaptive Force, Health Scaling
  • Core Items: Kraken Slayer → Berserker's Greaves → Guinsoo's Rageblade
  • Full Build: Add Nashor's Tooth, Zhonya's Hourglass, Rabadon's Deathcap
  • Ability Order: Q > E > W

Alternative Build (49.7% WR, 15,006 matches):

  • Runes: Press the Attack, Triumph, Legend: Haste, Cut Down + Magical Footwear, Jack Of All Trades
  • Core Items: Statikk Shiv → Sorcerer's Shoes → Essence Reaver
  • Full Build: Add Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap
  • Ability Order: Q > W > E

Key Tips:

  • Use mixed damage items (AD, AP, Attack Speed) to evolve multiple abilities
  • Position Ultimate (R) strategically in teamfights for survival
  • Cast Q when enemies are isolated from minions for maximum damage

Strong Against:

  • Mel (51.4% WR)
  • Jhin (50.3% WR)
  • Ezreal (50.2% WR)

Weak Against:

  • Nilah (42.4% WR)
  • Kog'Maw (42.9% WR)
  • Swain (43.7% WR)

Best Synergies:

  • Fiddlesticks (53.3% WR)
  • Amumu (52.2% WR)
  • Zoe (50.9% WR)

Situational Items:

  • Adjust defensive rune shards based on lane opponent (Armor vs AD, Magic Resist vs AP)
  • Build path should consider team composition and game state

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