
Kai'Sa ADC Build Guide: Best Runes, Items and Matchups (Patch 15.3)
Kai'Sa is a versatile ADC who excels with mixed damage builds, combining AD, AP, and attack speed. Here's a comprehensive guide to maximize her potential:
Most Popular Build (50.5% WR, 94,406 matches)
- Summoner Spells: Flash, Barrier
- Runes: Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace
- Secondary: Biscuit Delivery, Magical Footwear
- Shards: Attack Speed, Adaptive Force, Health Scaling
- Core Items: Kraken Slayer > Berserker's Greaves > Guinsoo's Rageblade
- Final Items: Nashor's Tooth, Zhonya's Hourglass, Rabadon's Deathcap
- Skill Order: Q > E > W
Alternative Build (49.7% WR, 14,701 matches)
- Summoner Spells: Flash, Barrier
- Runes: Press the Attack, Triumph, Legend: Haste, Cut Down
- Secondary: Magical Footwear, Jack Of All Trades
- Core Items: Statikk Shiv > Sorcerer's Shoes > Essence Reaver
- Final Items: Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap
- Skill Order: Q > W > E
Key Tips:
- Use Q when enemies are isolated for maximum damage
- Utilize R for repositioning and survival in teamfights
- Mix damage types to unlock evolved abilities
Best Matchups:
- Mel (51.5% WR)
- Jhin (50.3% WR)
- Ezreal (50.2% WR)
Worst Counters:
- Nilah (42.5% WR)
- Kog'Maw (43.0% WR)
- Swain (44.0% WR)
Best Supports:
- Fiddlesticks (53.2% WR)
- Amumu (52.5% WR)
- Braum (51.0% WR)
Remember to adjust your build based on team composition and matchups. Consider defensive items earlier if facing heavy burst damage.
Related Articles

Ambessa Mid: Complete Champion Guide & Pro Tips for Patch 15.4.1
