Kai'Sa ADC Build Guide: Best Runes, Items and Matchups (Patch 15.3)

Kai'Sa ADC Build Guide: Best Runes, Items and Matchups (Patch 15.3)

By Marcus Chen

February 17, 2025 at 02:17 PM

Kai'Sa is a versatile ADC who excels with mixed damage builds, combining AD, AP, and attack speed. Here's a comprehensive guide to maximize her potential:

Most Popular Build (50.5% WR, 94,406 matches)

  • Summoner Spells: Flash, Barrier
  • Runes: Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace
  • Secondary: Biscuit Delivery, Magical Footwear
  • Shards: Attack Speed, Adaptive Force, Health Scaling
  • Core Items: Kraken Slayer > Berserker's Greaves > Guinsoo's Rageblade
  • Final Items: Nashor's Tooth, Zhonya's Hourglass, Rabadon's Deathcap
  • Skill Order: Q > E > W

Alternative Build (49.7% WR, 14,701 matches)

  • Summoner Spells: Flash, Barrier
  • Runes: Press the Attack, Triumph, Legend: Haste, Cut Down
  • Secondary: Magical Footwear, Jack Of All Trades
  • Core Items: Statikk Shiv > Sorcerer's Shoes > Essence Reaver
  • Final Items: Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap
  • Skill Order: Q > W > E

Key Tips:

  • Use Q when enemies are isolated for maximum damage
  • Utilize R for repositioning and survival in teamfights
  • Mix damage types to unlock evolved abilities

Best Matchups:

  • Mel (51.5% WR)
  • Jhin (50.3% WR)
  • Ezreal (50.2% WR)

Worst Counters:

  • Nilah (42.5% WR)
  • Kog'Maw (43.0% WR)
  • Swain (44.0% WR)

Best Supports:

  • Fiddlesticks (53.2% WR)
  • Amumu (52.5% WR)
  • Braum (51.0% WR)

Remember to adjust your build based on team composition and matchups. Consider defensive items earlier if facing heavy burst damage.

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