Galio Mid Lane Rune Guide

Optimal Rune Setup (Patch 15.4):

• Primary: Resolve
• Secondary: Sorcery
• Win Rate: 49.8%
• Pick Rate: 48.2%
• Based on 33,548 matches

Best Matchups:

• Diana (55.7% WR)
• Katarina (54.4% WR)
• Malzahar (54.3% WR)
• Mel (54.0% WR)
• Akali (53.5% WR)
• Sylas (53.1% WR)

Challenging Matchups:

• Swain (42.9% WR)
• Anivia (45.8% WR)
• Ahri (46.2% WR)
• Veigar (46.3% WR)
• Vel'Koz (46.5% WR)
• Karma (46.9% WR)

Best Jungle Synergies:

• Amumu (55.2% WR)
• Bel'Veth (53.7% WR)
• Warwick (53.3% WR)
• Master Yi (53.0% WR)
• Darius (53.0% WR)
• Rengar (52.9% WR)

Essential Tips:

1. Post-6 Play: Use ultimate strategically as it's more utility-focused than combat-oriented
2. Wave Management: Keep wave closer to tower to facilitate jungler ganks
3. Roaming Setup: Clear wave with Q + E combo followed by empowered auto-attack before using ultimate

Optimal Rune Choices:

• Primary (Resolve):

  • Keystone: Aftershock
  • Slot 1: Demolish
  • Slot 2: Second Wind
  • Slot 3: Overgrowth

• Secondary (Sorcery):

  • Slot 1: Manaflow Band
  • Slot 2: Transcendence

This setup provides optimal balance between durability and mana sustain while maximizing Galio's roaming potential and teamfight presence.

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