Elise Support Runes: Domination and Precision Build Guide 15.4

Elise Support Runes: Domination and Precision Build Guide 15.4

By Marcus Chen

February 24, 2025 at 02:02 AM

Support Elise excels with a Domination/Precision rune setup, achieving a 52.0% win rate in patch 15.4 with a 64.5% pick rate across 10,775 matches.

Primary Runes (Domination)

  • Keystone: Electrocute
  • Sudden Impact
  • Deep Ward
  • Treasure Hunter

Secondary Runes (Precision)

  • Triumph
  • Coup de Grace

Strong Against:

  • Zoe (61.1% WR)
  • Tahm Kench (60.2% WR)
  • Swain (60.0% WR)
  • Brand (60.0% WR)
  • Shaco (58.7% WR)
  • Ashe (58.3% WR)

Weak Against:

  • Taric (37.2% WR)
  • Sona (41.7% WR)
  • Maokai (45.4% WR)
  • Braum (46.4% WR)
  • Renata Glasc (47.7% WR)
  • Vel'Koz (48.2% WR)

Best ADC Synergies:

  • Aphelios (55.9% WR)
  • Ashe (55.3% WR)
  • Twitch (52.7% WR)
  • Sivir (52.0% WR)
  • Jinx (52.0% WR)
  • Ezreal (51.9% WR)

This rune setup maximizes Elise's early game pressure and burst potential while providing sustain through Triumph and additional damage through Coup de Grace. The combination is particularly effective for aggressive lane control and roaming opportunities.

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