Optimizing Cassiopeia's runes and matchups for optimal performance in the bot lane during patch 14.23.

The most effective rune combination uses Precision (Primary) and Sorcery (Secondary), achieving a 54.7% win rate across 4,048 matches.

Key Rune Selections:

• Primary (Precision): Conqueror, Presence of Mind, Legend: Haste, Cut Down
• Secondary (Sorcery): Manaflow Band, Transcendence

Favorable Matchups:

• Smolder (62.5% WR)
• Corki (57.4% WR)
• Swain (56.4% WR)
• Yone (56.0% WR)
• Yasuo (55.7% WR)
• Kassadin (55.7% WR)

Challenging Matchups:

• Vel'Koz (46.5% WR)
• Syndra (46.6% WR)
• Qiyana (46.7% WR)
• Naafiri (46.8% WR)
• Zoe (47.1% WR)
• Anivia (47.3% WR)

Best Jungle Synergies:

• Rammus (58.7% WR)
• Rek'Sai (57.2% WR)
• Ekko (55.4% WR)
• Bel'Veth (55.3% WR)
• Diana (55.2% WR)
• Xin Zhao (54.7% WR)

Essential Tips:

1. Monitor mana consumption during early trades
2. Initiate trades only after landing Q ability
3. Prioritize ability-based trades over auto-attacks against ADCs
4. Use Q-E combo for optimal damage output

Remember to adapt your playstyle based on matchups and team composition for best results.

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