Yasuo Mid Runes Guide

Precision / Resolve remains the optimal rune combination for Yasuo in patch 15.6, maintaining a 50.2% win rate with 75.4% pick rate across 2,248 matches.

Primary Runes (Precision)

• Keystone: Lethal Tempo
• Triumph
• Legend: Alacrity
• Cut Down

Secondary Runes (Resolve)

• Bone Plating
• Overgrowth

Strong Matchups

• Tristana (73.3% WR)
• Swain (64.7% WR)
• Talon (63.9% WR)
• Fizz (62.2% WR)
• Jayce (61.9% WR)
• Sylas (60.6% WR)

Weak Matchups

• Kayle (31.3% WR)
• Annie (33.3% WR)
• Renekton (35.7% WR)
• Taliyah (36.5% WR)
• Galio (37.9% WR)
• Azir (38.9% WR)

Best Duo Synergies

• Diana (51.5% WR)
• Lee Sin (50.5% WR)

Essential Tips

1. Use E through minion waves strategically, always leaving one minion as an escape route
2. Time your ultimate carefully - avoid engaging in unfavorable situations
3. Conserve Windwall for crucial moments, especially during ganks or against global ultimates

This optimized rune setup maximizes Yasuo's lane presence and scaling potential while providing necessary defensive options through the Resolve tree.

Note: For additional build optimization and matchup-specific strategies, consider checking professional player builds and participating in Yasuo main communities.

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