Best Vayne Bot Build Guide: Builds & Runes for Season 15 [55.1% WR]

Best Vayne Bot Build Guide: Builds & Runes for Season 15 [55.1% WR]

By Marcus Chen

February 23, 2025 at 12:26 PM

Vayne bot lane is a scaling hypercarry who excels at dealing consistent single-target damage. While weak early, she becomes extremely powerful in late game.

Core Build:

  • Summoner Spells: Flash, Barrier
  • Core Items: Blade of The Ruined King → Berserker's Greaves → Guinsoo's Rageblade
  • Full Build: Add Terminus → Jak'Sho → Wit's End
  • Skill Order: Q > W > E

Recommended Runes:

  • Primary: Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace
  • Secondary: Conditioning, Overgrowth
  • Shards: Attack Speed, Adaptive Force, Health Scaling

Key Matchups: Strong Against:

  • Mel (60.1% WR)
  • Ziggs (54.4% WR)
  • Kai'Sa (54.3% WR)
  • Ezreal (54.2% WR)

Weak Against:

  • Nilah (45.8% WR)
  • Aphelios (49.2% WR)
  • Yasuo (49.6% WR)
  • Caitlyn (49.8% WR)

Best Support Synergies:

  • Zyra (57.9% WR)
  • Soraka (56.8% WR)
  • Milio (55.7% WR)
  • Zilean (55.7% WR)

Key Tips:

  • Play safe early and focus on farming
  • Always aim to proc W passive with 3 consecutive auto attacks
  • Position carefully in teamfights and save Q for defensive plays
  • Build order can be adjusted based on matchups and team compositions

Alternative Builds:

  1. Crit Build:

    • Yun Tal Wildarrows → Berserker's → Infinity Edge → Phantom Dancer → Lord Dominik's → Bloodthirster
    • Takes Press the Attack instead of Lethal Tempo
  2. Tank Shred Build:

    • Kraken Slayer → Berserker's → Guinsoo's → Terminus → Jak'Sho → Wit's End

The most successful build currently maintains a 55.1% win rate over 8,831 matches in Emerald+ elo.

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