Kai'Sa Top Lane Runes Guide

Lethal Tempo is the optimal keystone for Kai'Sa Top, maintaining a 43.2% win rate in patch 15.4 across 384 matches. This build has a considerable 51.2% pick rate.

Primary Runes (Precision):

• Lethal Tempo
• Triumph
• Legend: Alacrity
• Cut Down

Secondary Runes (Inspiration):

• Magical Footwear
• Biscuit Delivery

Best Matchups:

• Mel (54.3% WR)
• Ziggs (51.2% WR)
• Jhin (51.1% WR)
• Lucian (50.7% WR)
• Ezreal (50.6% WR)
• Kalista (49.9% WR)

Challenging Matchups:

• Kog'Maw (42.3% WR)
• Nilah (43.7% WR)
• Aphelios (44.1% WR)
• Vayne (45.5% WR)
• Jinx (46.0% WR)
• Yasuo (46.3% WR)

Best Support Synergies:

• Sona (52.6% WR)
• Vel'Koz (52.0% WR)
• Amumu (51.9% WR)
• LeBlanc (51.6% WR)
• Poppy (51.4% WR)
• Zoe (51.0% WR)

This build optimizes Kai'Sa's early game trading potential while ensuring scaling into late game through attack speed and sustain. The Inspiration secondary tree provides additional lane sustain and early game economy through free boots and biscuits.

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