Senna Support Runes Guide

Optimal Rune Setup: Resolve/Precision

• Current Win Rate: 52.1%
• Pick Rate: 44.5%
• Based on 8,179 matches in Patch 14.23

Primary Tree (Resolve)

• Keystone: Grasp of the Undying
• Font of Life
• Second Wind
• Revitalize

Secondary Tree (Precision)

• Presence of Mind
• Legend: Alacrity

Strong Against:

• Swain (61.9% WR)
• Brand (60.7% WR)
• Ashe (58.0% WR)
• Sylas (57.4% WR)
• Tahm Kench (57.0% WR)
• Pantheon (56.2% WR)

Weak Against:

• Shaco (43.2% WR)
• Zoe (43.8% WR)
• Lux (46.8% WR)
• LeBlanc (47.3% WR)
• Nami (47.5% WR)
• Zilean (47.7% WR)

Best ADC Synergies:

• Nilah (61.1% WR)
• Xayah (54.7% WR)
• Jhin (54.2% WR)
• Kog'Maw (54.0% WR)
• Vayne (53.9% WR)
• Draven (53.8% WR)

Essential Tips:

1. Avoid using ultimate (R) mid-combo as it leaves you vulnerable and reduces DPS
2. Save your E for escape or gank situations rather than trading
3. Play aggressively at level 1 to establish lane dominance

This setup optimizes Senna's support role while maintaining strong scaling and utility throughout the game.

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