
Best Nilah Runes Guide for Bot Lane (52.5% WR)
Nilah Runes (Season 15 Optimal Setup)
The optimal rune setup for Nilah in patch 15.4 achieves a 52.5% win rate with a 40.9% pick rate across 5,874 matches.
Primary Tree (Precision):
- Keystone: Conqueror
- Triumph
- Legend: Alacrity
- Last Stand
Secondary Tree (Domination):
- Sudden Impact
- Treasure Hunter
Strong Against:
- Twitch (58.6% WR)
- Ezreal (57.0% WR)
- Kai'Sa (57.0% WR)
- Samira (56.6% WR)
- Aphelios (55.8% WR)
- Ashe (55.2% WR)
Weak Against:
- Kog'Maw (44.8% WR)
- Xayah (46.0% WR)
- Hwei (48.0% WR)
- Smolder (48.2% WR)
- Sivir (49.5% WR)
- Jinx (49.6% WR)
Best Support Synergies:
- Taric (59.5% WR)
- Senna (57.6% WR)
- Karma (57.3% WR)
- Alistar (56.6% WR)
- Thresh (56.4% WR)
- Blitzcrank (56.3% WR)
Pro Tips:
- Maintain two E stacks for escape options during aggressive plays
- Leverage your passive XP advantage for level 6 power spike
- Position for grouped fights to maximize ultimate effectiveness with E-R combo
Related Champions:
- Difficulty: Average to Severe
- Playstyle: Aggressive melee ADC
Note: For additional build variations and in-depth statistics, consult professional player builds and community resources.
Related Articles

Mel Mid Lane Build Guide & Best Runes - Patch 15.5
