For optimal performance in Bot lane, Heimerdinger's most effective rune combination is Sorcery primary with Precision secondary, boasting a 59.0% win rate across 446 matches in patch 15.5.

Primary Runes (Sorcery)

• Keystone: Arcane Comet
• Axiom Arcanist
• Transcendence
• Gathering Storm

Secondary Runes (Precision)

• Presence of Mind
• Legend: Haste

Strong Matchups:

• Trundle (62.5%)
• Shen (62.3%)
• Volibear (60.7%)
• Pantheon (60.3%)
• Mordekaiser (59.1%)
• Warwick (58.5%)

Weak Matchups:

• Akali (39.8%)
• Kled (40.9%)
• Yasuo (42.3%)
• Ornn (43.6%)
• Aurora (44.6%)
• Zed (45.3%)

Best Duo Synergies:

• Master Yi (57.0%)
• Hecarim (56.9%)
• Kindred (56.8%)
• Xin Zhao (56.3%)
• Darius (56.2%)
• Wukong (55.2%)

Essential Tips:

1. Place Turrets (Q) before laning phase begins to conserve mana and secure early push advantage
2. Always engage enemies within Turret (Q) range for maximum damage output
3. When casting bomb (E), aim slightly behind enemies for higher stun success rate, especially within Turret range

These strategies maximize Heimerdinger's lane presence and damage potential while maintaining proper mana management and positioning.

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